BDBM50271978 CHEMBL499885::methyl 4-(2-fluoro-4-(3-(2-(4-fluorophenyl)acetyl)ureido)phenoxy)-1H-pyrrolo[2,3-b]pyridine-3-carboxylate

SMILES COC(=O)c1c[nH]c2nccc(Oc3ccc(NC(=O)NC(=O)Cc4ccc(F)cc4)cc3F)c12

InChI Key InChIKey=DXKBUNHVRDQHHI-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50271978   

TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50271978(CHEMBL499885 | methyl 4-(2-fluoro-4-(3-(2-(4-fluor...)
Affinity DataIC50:  5nMAssay Description:Inhibition of human c-METMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50271978(CHEMBL499885 | methyl 4-(2-fluoro-4-(3-(2-(4-fluor...)
Affinity DataIC50:  5nMAssay Description:Inhibition of Met kinase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed