BDBM50272829 (+/-)-1-(4-(2,4-difluorophenyl)thiazol-2-yl)-2-(2-methylcyclohexylidene)hydrazine::CHEMBL1240558::CHEMBL498505

SMILES CC1CCCCC1=NNc1nc(cs1)-c1ccc(F)cc1F

InChI Key InChIKey=GBSDYRSNVCORPF-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50272829   

TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50272829((+/-)-1-(4-(2,4-difluorophenyl)thiazol-2-yl)-2-(2-...)
Affinity DataIC50:  3.80E+4nMAssay Description:Inhibition of human recombinant MAOAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50272829((+/-)-1-(4-(2,4-difluorophenyl)thiazol-2-yl)-2-(2-...)
Affinity DataIC50:  14.2nMAssay Description:Inhibition of human recombinant MAOBMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50272829((+/-)-1-(4-(2,4-difluorophenyl)thiazol-2-yl)-2-(2-...)
Affinity DataIC50:  3.80E+4nMAssay Description:Inhibition of human recombinant MAOA expressed in baculovirus infected BTI-TN-5B1-4 insect cells assessed as hydrogen peroxide production from p-tyra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50272829((+/-)-1-(4-(2,4-difluorophenyl)thiazol-2-yl)-2-(2-...)
Affinity DataIC50:  14nMAssay Description:Inhibition of human recombinant MAOB expressed in baculovirus infected insect BTI-TN-5B1-4 cells assessed as production of hydrogen peroxide from p-t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50272829((+/-)-1-(4-(2,4-difluorophenyl)thiazol-2-yl)-2-(2-...)
Affinity DataIC50:  14nMAssay Description:Inhibition of human recombinant MAOB expressed in baculovirus infected BTI-TN-5B1-4 insect cells assessed as hydrogen peroxide production from p-tyra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50272829((+/-)-1-(4-(2,4-difluorophenyl)thiazol-2-yl)-2-(2-...)
Affinity DataIC50:  3.80E+4nMAssay Description:Inhibition of human recombinant MAOA expressed in baculovirus infected insect BTI-TN-5B1-4 cells assessed as production of hydrogen peroxide from p-t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed