BDBM50272866 1-(4-(2,4-difluorophenyl)thiazol-2-yl)-2-((R)-2-methylcyclohexylidene)hydrazine::CHEMBL1242991::CHEMBL497676

SMILES C[C@@H]1CCCCC1=NNc1nc(cs1)-c1ccc(F)cc1F

InChI Key InChIKey=GBSDYRSNVCORPF-SNVBAGLBSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50272866   

TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50272866(1-(4-(2,4-difluorophenyl)thiazol-2-yl)-2-((R)-2-me...)
Affinity DataIC50:  6.83E+3nMAssay Description:Inhibition of human recombinant MAOAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50272866(1-(4-(2,4-difluorophenyl)thiazol-2-yl)-2-((R)-2-me...)
Affinity DataIC50:  30.1nMAssay Description:Inhibition of human recombinant MAOBMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50272866(1-(4-(2,4-difluorophenyl)thiazol-2-yl)-2-((R)-2-me...)
Affinity DataIC50:  6.83E+3nMAssay Description:Inhibition of human recombinant MAOA expressed in baculovirus infected BTI-TN-5B1-4 insect cells assessed as hydrogen peroxide production from p-tyra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50272866(1-(4-(2,4-difluorophenyl)thiazol-2-yl)-2-((R)-2-me...)
Affinity DataIC50:  30nMAssay Description:Inhibition of human recombinant MAOB expressed in baculovirus infected insect BTI-TN-5B1-4 cells assessed as production of hydrogen peroxide from p-t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] B(Homo sapiens (Human))
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50272866(1-(4-(2,4-difluorophenyl)thiazol-2-yl)-2-((R)-2-me...)
Affinity DataIC50:  47.9nMAssay Description:Inhibition of human recombinant MAOB expressed in baculovirus infected BTI-TN-5B1-4 insect cells assessed as hydrogen peroxide production from p-tyra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAmine oxidase [flavin-containing] A(Homo sapiens (Human))
Sapienza University Of Rome

Curated by ChEMBL
LigandPNGBDBM50272866(1-(4-(2,4-difluorophenyl)thiazol-2-yl)-2-((R)-2-me...)
Affinity DataIC50:  6.83E+3nMAssay Description:Inhibition of human recombinant MAOA expressed in baculovirus infected insect BTI-TN-5B1-4 cells assessed as production of hydrogen peroxide from p-t...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed