BDBM50272952 CHEMBL4126054

SMILES NC(=O)c1ccc(Oc2cccc(c2)C(N)=O)cc1

InChI Key InChIKey=PMOXYDXLQIUWHL-UHFFFAOYSA-N

Data  9 IC50

PDB links: 1 PDB ID matches this monomer.

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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50272952   

TargetProtein mono-ADP-ribosyltransferase PARP10(Homo sapiens (Human))
Mcdaniel College

Curated by ChEMBL
LigandPNGBDBM50272952(CHEMBL4126054)
Affinity DataIC50:  513nMAssay Description:Inhibition of full length recombinant His6-tagged human PARP10 expressed in Escherichia coli BL21(DE3) preincubated for 15 mins followed by biotinyla...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein mono-ADP-ribosyltransferase PARP10(Homo sapiens (Human))
Mcdaniel College

Curated by ChEMBL
LigandPNGBDBM50272952(CHEMBL4126054)
Affinity DataIC50:  510nMAssay Description:Inhibition of full length recombinant His6-tagged human PARP10 expressed in Escherichia coli BL21(DE3) preincubated for 15 mins followed by biotinyla...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein mono-ADP-ribosyltransferase PARP10(Homo sapiens (Human))
Mcdaniel College

Curated by ChEMBL
LigandPNGBDBM50272952(CHEMBL4126054)
Affinity DataIC50:  480nMAssay Description:Inhibition of C-terminal his-tagged human PARP10 expressed in Escherichia coli Rosette2 (DE3)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetProtein mono-ADP-ribosyltransferase PARP15(Homo sapiens (Human))
University Of Perugia

Curated by ChEMBL
LigandPNGBDBM50272952(CHEMBL4126054)
Affinity DataIC50:  1.70E+3nMAssay Description:Inhibition of N-terminal his-tagged human PARP15 expressed in Escherichia coli Rosette2 (DE3)More data for this Ligand-Target Pair
TargetPoly [ADP-ribose] polymerase 2(Homo sapiens (Human))
University Of Perugia

Curated by ChEMBL
LigandPNGBDBM50272952(CHEMBL4126054)
Affinity DataIC50:  1.70E+3nMAssay Description:Inhibition of N-terminal his-tagged human PARP2 expressed in Escherichia coli Rosette2 (DE3)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetPoly [ADP-ribose] polymerase tankyrase-1(Homo sapiens (Human))
University Of Perugia

Curated by ChEMBL
LigandPNGBDBM50272952(CHEMBL4126054)
Affinity DataIC50:  2.10E+4nMAssay Description:Inhibition of N-terminal his-tagged human TNKS1 expressed in Escherichia coli Rosette2 (DE3)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetPoly [ADP-ribose] polymerase tankyrase-2(Homo sapiens (Human))
University Of Perugia

Curated by ChEMBL
LigandPNGBDBM50272952(CHEMBL4126054)
Affinity DataIC50:  6.50E+3nMAssay Description:Inhibition of N-terminal his-tagged human TNKS2 expressed in Escherichia coli Rosette2 (DE3)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetPoly [ADP-ribose] polymerase 1(Homo sapiens (Human))
University Of Perugia

Curated by ChEMBL
LigandPNGBDBM50272952(CHEMBL4126054)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of N-terminal his-tagged human PARP1 expressed in Escherichia coli Rosette2 (DE3)More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetProtein mono-ADP-ribosyltransferase PARP14(Homo sapiens (Human))
University Of Perugia

Curated by ChEMBL
LigandPNGBDBM50272952(CHEMBL4126054)
Affinity DataIC50:  4.10E+4nMAssay Description:Inhibition of N-terminal his-tagged human PARP14 expressed in Escherichia coli Rosette2 (DE3)More data for this Ligand-Target Pair
In DepthDetails PubMed