BDBM50273571 CHEMBL514409::Hesperadin::N-(2-oxo-3-(phenyl(4-(piperidin-1-ylmethyl)phenylamino)methylene)indolin-5-yl)ethanesulfonamide::TCMDC-135395
SMILES CCS(=O)(=O)Nc1ccc2NC(=O)C(C(=Nc3ccc(CN4CCCCC4)cc3)c3ccccc3)c2c1
InChI Key InChIKey=SGZZQKMOFHIDKW-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 11 hits for monomerid = 50273571
Affinity DataKd: 52nMAssay Description:Binding affinity to human LTKMore data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase ROS(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataKd: 77nMAssay Description:Binding affinity to human ROSMore data for this Ligand-Target Pair
Affinity DataKd: 33nMAssay Description:Binding affinity to human FAKMore data for this Ligand-Target Pair
Affinity DataKd: 10nMAssay Description:Binding affinity to human PYK2More data for this Ligand-Target Pair
TargetNon-receptor tyrosine-protein kinase TYK2(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataKd: 75nMAssay Description:Binding affinity to human TYK2More data for this Ligand-Target Pair
Affinity DataKd: 31nMAssay Description:Binding affinity to human MSK1More data for this Ligand-Target Pair
Affinity DataKd: 94nMAssay Description:Binding affinity to human MSK2More data for this Ligand-Target Pair
Target5'-AMP-activated protein kinase catalytic subunit alpha-1(Homo sapiens (Human))
Glaxosmithkline
Curated by ChEMBL
Glaxosmithkline
Curated by ChEMBL
Affinity DataKd: 19nMAssay Description:Binding affinity to human AMPKA1More data for this Ligand-Target Pair
Affinity DataKd: 92nMAssay Description:Binding affinity to human BRSK2More data for this Ligand-Target Pair
Affinity DataKd: 1.40E+4nMAssay Description:Binding affinity to human PAK2More data for this Ligand-Target Pair
Affinity DataKd: 149nMAssay Description:Binding affinity to human FESMore data for this Ligand-Target Pair