BDBM50273862 CHEMBL462305::N-(5-Hydroxy-adamantan-2-yl)-2-m-tolyl-isobutyramide

SMILES Cc1cccc(c1)C(C)(C)C(=O)NC1C2CC3CC1CC(O)(C3)C2

InChI Key InChIKey=KALCNQQOYMSHHC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50273862   

Target11-beta-hydroxysteroid dehydrogenase 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50273862(CHEMBL462305 | N-(5-Hydroxy-adamantan-2-yl)-2-m-to...)
Affinity DataIC50:  5nMAssay Description:Inhibition of human 11beta-HSD1 expressed in CHO cells assessed as conversion of cortisone to cortisol by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed