BDBM50274041 CHEMBL4127967

SMILES CC(C)C[C@H](NC(=O)[C@@H](N)Cc1ccccc1)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](CCCCN)CS(F)(=O)=O

InChI Key InChIKey=YZEZRWGWUQTWOH-ZJZGAYNASA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50274041   

TargetProteasome subunit beta type-10(Homo sapiens (Human))
University Of Glasgow

Curated by ChEMBL
LigandPNGBDBM50274041(CHEMBL4127967)
Affinity DataIC50:  300nMAssay Description:Inhibition of human 20S immunoproteasome beta-2 using Bz-VGR-AMC as substrate after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-2(Homo sapiens (Human))
University Of Glasgow

Curated by ChEMBL
LigandPNGBDBM50274041(CHEMBL4127967)
Affinity DataIC50:  470nMAssay Description:Inhibition of human 20S constitutive proteasome beta-2 using Bz-VGR-AMC as substrate after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-5(Homo sapiens (Human))
University Of Glasgow

Curated by ChEMBL
LigandPNGBDBM50274041(CHEMBL4127967)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human 20S constitutive proteasome beta-5 using Suc-LLVY-AMC as substrate after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProteasome subunit beta type-8(Homo sapiens (Human))
University Of Glasgow

Curated by ChEMBL
LigandPNGBDBM50274041(CHEMBL4127967)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human 20S immunoproteasome beta-5 using Suc-LLVY-AMC as substrate after 60 mins by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed