BDBM50274989 (Z)-1-((5-Methoxybenzo[b]thiophen-2-yl)methylene)-6-methyl-4-thioxo-4,5-dihydrofuro[3,4-c]pyridin-3(1H)-one::CHEMBL457732

SMILES COc1ccc2sc(\C=C3/OC(=O)c4c3cc(C)[nH]c4=S)cc2c1

InChI Key InChIKey=LPZMODLAXACSTA-ZSOIEALJSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50274989   

TargetPerforin-1(Homo sapiens (Human))
University Of Auckland

Curated by ChEMBL
LigandPNGBDBM50274989((Z)-1-((5-Methoxybenzo[b]thiophen-2-yl)methylene)-...)
Affinity DataIC50:  1.31E+4nMAssay Description:Inhibition of recombinant perforin (unknown origin)-mediated lysis of human Jurkat T cells by 51Cr release assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed