BDBM50275500 4-fluoro-2-(4-fluorophenyl)-3-(pyridin-4-yl)pyrazolo[1,5-a]pyridine::CHEMBL509189::D3RKN_43

SMILES Fc1ccc(cc1)-c1nn2cccc(F)c2c1-c1ccncc1

InChI Key InChIKey=VFCFJSWYTMMESK-UHFFFAOYSA-N

Data  1 IC50  2 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50275500   

TargetMitogen-activated protein kinase 14(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50275500(4-fluoro-2-(4-fluorophenyl)-3-(pyridin-4-yl)pyrazo...)
Affinity DataIC50:  240nMAssay Description:Inhibition of GST-fused p38alpha (unknown origin) expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
D3R/Abbott

LigandPNGBDBM50275500(4-fluoro-2-(4-fluorophenyl)-3-(pyridin-4-yl)pyrazo...)
Affinity DataKd:  1.00E+4nMAssay Description:D3R2022More data for this Ligand-Target Pair
In DepthDetails PubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
D3R/Abbott

LigandPNGBDBM50275500(4-fluoro-2-(4-fluorophenyl)-3-(pyridin-4-yl)pyrazo...)
Affinity DataKd:  1.00E+4nMAssay Description:D3R2021More data for this Ligand-Target Pair
In DepthDetails PubMed