BDBM50275938 CHEMBL4126223

SMILES CN(C)\N=C1\CN(CC(=O)Nc2cccc(c2)-c2cnn(C)c2)C(=O)C(Cc2ccccc2C#N)CN1

InChI Key InChIKey=UCOBXQMPYIMXQT-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50275938   

TargetKallikrein-7(Mus musculus)
Asubio Pharma

Curated by ChEMBL
LigandPNGBDBM50275938(CHEMBL4126223)
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of mouse KLK7 using MOCAcArg-Pro-Lys-Pro-Val-Glu-Nva-Trp-Arg-Lys(Dnp)-NH2 as substrate preincubated for 10 mins followed by substrate addi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKallikrein-7(Homo sapiens (Human))
Asubio Pharma

Curated by ChEMBL
LigandPNGBDBM50275938(CHEMBL4126223)
Affinity DataIC50:  1.70E+4nMAssay Description:Inhibition of recombinant human C-terminal His10-tagged KLK7 (E23 to H252 residues) using MOCAcArg-Pro-Lys-Pro-Val-Glu-Nva-Trp-Arg-Lys(Dnp)-NH2 as su...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed