BDBM50276064 CHEMBL470780::N-(3,5-dimethylphenyl)-4-(5-methylthiazol-2-yl)pyrimidin-2-amine
SMILES Cc1cnc(s1)-c1ccnc(Nc2cc(C)cc(C)c2)n1
InChI Key InChIKey=LZQTVVQZQUWSAI-UHFFFAOYSA-N
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 5 hits for monomerid = 50276064
Affinity DataKi: 23nMAssay Description:Inhibition of SYK (unknown origin)More data for this Ligand-Target Pair
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Vertex Pharmaceuticals
Curated by ChEMBL
Vertex Pharmaceuticals
Curated by ChEMBL
Affinity DataKi: 348nMAssay Description:Inhibition of SRC (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 410nMAssay Description:Inhibition of ZAP70 (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 1.10E+3nMAssay Description:Inhibition of CDK2 (unknown origin)More data for this Ligand-Target Pair
Affinity DataIC50: 200nMAssay Description:Inhibition of SYK (unknown origin)-mediated FCepsilonRI signaling activity by mast cell degranulation assayMore data for this Ligand-Target Pair