BDBM50276374 CHEMBL4126946
SMILES OC[C@H]1OCC(=O)C[C@@H]1O
InChI Key InChIKey=ATVAXTJIRCBICU-NTSWFWBYSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50276374
TargetNACHT, LRR and PYD domains-containing protein 3(Mus musculus)
The Noguchi Institute
Curated by ChEMBL
The Noguchi Institute
Curated by ChEMBL
Affinity DataIC50: 1.60E+6nMAssay Description:Inhibition of nigericin-induced NLRP3 inflammasome activation in C57BL/6 mouse bone marrow derived macrophages assessed as reduction in LPS-stimulate...More data for this Ligand-Target Pair
TargetNACHT, LRR and PYD domains-containing protein 3(Homo sapiens (Human))
The Noguchi Institute
Curated by ChEMBL
The Noguchi Institute
Curated by ChEMBL
Affinity DataIC50: 2.30E+6nMAssay Description:Inhibition of nigericin-induced NLRP3 inflammasome activation in PMA-differentiated human THP1 cells assessed as reduction in LPS-stimulated IL-1beta...More data for this Ligand-Target Pair