BDBM50276791 CHEMBL4164891

SMILES FC(F)(F)c1nc2c(cccc2c(Cl)c1Br)-c1cccc(c1)C#N

InChI Key InChIKey=TXFBXFRILQIUEL-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50276791   

TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 1(Homo sapiens (Human))
Universit£T Rostock

Curated by ChEMBL
LigandPNGBDBM50276791(CHEMBL4164891)
Affinity DataIC50:  350nMAssay Description:Inhibition of human full length NPP1 expressed in African green monkey COS7 cell membrane fraction using p-nitrophenyl-5'-thymidine monophosphate as ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEctonucleotide pyrophosphatase/phosphodiesterase family member 3(Homo sapiens (Human))
Universit£T Rostock

Curated by ChEMBL
LigandPNGBDBM50276791(CHEMBL4164891)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human full length NPP3 expressed in African green monkey COS7 cell membrane fraction using p-nitrophenyl-5'-thymidine monophosphate as ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEctonucleoside triphosphate diphosphohydrolase 8(Homo sapiens (Human))
Universit£T Rostock

Curated by ChEMBL
LigandPNGBDBM50276791(CHEMBL4164891)
Affinity DataIC50: >3.00E+5nMAssay Description:Inhibition of human NTPDase8 expressed in African green monkey COS7 cell membrane fraction using ATP as substrate preincubated for 10 mins followed b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEctonucleoside triphosphate diphosphohydrolase 3(Homo sapiens (Human))
Universit£T Rostock

Curated by ChEMBL
LigandPNGBDBM50276791(CHEMBL4164891)
Affinity DataIC50: >3.00E+5nMAssay Description:Inhibition of human NTPDase3 expressed in African green monkey COS7 cell membrane fraction using ATP as substrate preincubated for 10 mins followed b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEctonucleoside triphosphate diphosphohydrolase 2(Homo sapiens (Human))
Universit£T Rostock

Curated by ChEMBL
LigandPNGBDBM50276791(CHEMBL4164891)
Affinity DataIC50: >3.00E+5nMAssay Description:Inhibition of human NTPDase2 expressed in African green monkey COS7 cell membrane fraction using ATP as substrate preincubated for 10 mins followed b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetEctonucleoside triphosphate diphosphohydrolase 1(Homo sapiens (Human))
Universit£T Rostock

Curated by ChEMBL
LigandPNGBDBM50276791(CHEMBL4164891)
Affinity DataIC50: >3.00E+5nMAssay Description:Inhibition of human NTPDase1 expressed in African green monkey COS7 cell membrane fraction using ATP as substrate preincubated for 10 mins followed b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed