BDBM50276995 1-(2-(3-(3-chlorophenyl)-4-oxo-3,4-dihydroquinazolin-2-ylthio)-2-phenylacetyl)piperidine-4-carboxamide::CHEMBL460209

SMILES NC(=O)C1CCN(CC1)C(=O)C(Sc1nc2ccccc2c(=O)n1-c1cccc(Cl)c1)c1ccccc1

InChI Key InChIKey=DGNIAKAILQEBDR-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50276995   

TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50276995(1-(2-(3-(3-chlorophenyl)-4-oxo-3,4-dihydroquinazol...)
Affinity DataIC50:  2.10E+4nMAssay Description:Inhibition of C-terminal 6-His tagged human Chk1 by HTRF assay in presence of 0.1 mM ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed