BDBM50277001 3-(3-chlorophenyl)-2-((R)-1-oxo-1-((S)-2,8-diazaspiro[5.5]undecan-2-yl)hexan-2-ylthio)quinazolin-4(3H)-one::CHEMBL460853

SMILES CCCC[C@@H](Sc1nc2ccccc2c(=O)n1-c1cccc(Cl)c1)C(=O)N1CCC[C@]2(CCCNC2)C1

InChI Key InChIKey=GMBUMIBZLYNLLU-IRPSRAIASA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50277001   

TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50277001(3-(3-chlorophenyl)-2-((R)-1-oxo-1-((S)-2,8-diazasp...)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibition of C-terminal 6-His tagged human Chk1 by HTRF assay in presence of 0.1 mM ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed