BDBM50277029 2-(1-(4,4-diphenylpiperidin-1-yl)-1-oxohexan-2-ylthio)-3-phenylquinazolin-4(3H)-one::CHEMBL445683

SMILES CCCCC(Sc1nc2ccccc2c(=O)n1-c1ccccc1)C(=O)N1CCC(CC1)(c1ccccc1)c1ccccc1

InChI Key InChIKey=DXGYCOMKUQYCRH-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50277029   

TargetSerine/threonine-protein kinase Chk1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50277029(2-(1-(4,4-diphenylpiperidin-1-yl)-1-oxohexan-2-ylt...)
Affinity DataIC50:  4.50E+3nMAssay Description:Inhibition of C-terminal 6-His tagged human Chk1 by HTRF assay in presence of 0.1 mM ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed