BDBM50277972 CHEMBL519503::[5-(6-Amino-9-phenethyl-9H-purin-8-yl)-furan-2-yl]-phosphonic Acid

SMILES Nc1ncnc2n(CCc3ccccc3)c(nc12)-c1ccc(o1)P(O)(O)=O

InChI Key InChIKey=DVUPMKJBTAEKFB-UHFFFAOYSA-N

Data  4 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50277972   

TargetFructose-1,6-bisphosphatase 1(Homo sapiens (Human))
Metabasis Therapeutics

Curated by ChEMBL
LigandPNGBDBM50277972(CHEMBL519503 | [5-(6-Amino-9-phenethyl-9H-purin-8-...)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibition of human liver FBPase expressed in Escherichia coli by spectrophotometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetFructose-1,6-bisphosphatase 1(Rattus norvegicus)
Metabasis Therapeutics

Curated by ChEMBL
LigandPNGBDBM50277972(CHEMBL519503 | [5-(6-Amino-9-phenethyl-9H-purin-8-...)
Affinity DataIC50:  4.00E+4nMAssay Description:Inhibition of rat liver FBPaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGlycogen phosphorylase, muscle form(Oryctolagus cuniculus (rabbit))
Metabasis Therapeutics

Curated by ChEMBL
LigandPNGBDBM50277972(CHEMBL519503 | [5-(6-Amino-9-phenethyl-9H-purin-8-...)
Affinity DataEC50: >2.50E+5nMAssay Description:Inhibition of rabbit muscle glycogen phosphorylaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenosine kinase(Homo sapiens (Human))
Metabasis Therapeutics

Curated by ChEMBL
LigandPNGBDBM50277972(CHEMBL519503 | [5-(6-Amino-9-phenethyl-9H-purin-8-...)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of human recombinant adenosine kinase expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAdenylate kinase isoenzyme 1(Oryctolagus cuniculus)
Metabasis Therapeutics

Curated by ChEMBL
LigandPNGBDBM50277972(CHEMBL519503 | [5-(6-Amino-9-phenethyl-9H-purin-8-...)
Affinity DataIC50: >5.00E+5nMAssay Description:Inhibition of rabbit muscle adenylate kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed