BDBM50278145 CHEMBL469546::N-(2,4-dichlorobenzyl)-1-(mesitylsulfonyl)piperidine-4-carboxamide::cid_1306384

SMILES Cc1cc(C)c(c(C)c1)S(=O)(=O)N1CCC(CC1)C(=O)NCc1ccc(Cl)cc1Cl

InChI Key InChIKey=HRKVSQNBSGFSQY-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50278145   

TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
Columbia University Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM50278145(CHEMBL469546 | N-(2,4-dichlorobenzyl)-1-(mesitylsu...)
Affinity DataIC50:  8.10nMAssay Description:Data Source: Columbia University Molecular Screening Center Source (MLSCN Center Name): Columbia University Molecular Screening Center Center Affilia...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
Columbia University Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM50278145(CHEMBL469546 | N-(2,4-dichlorobenzyl)-1-(mesitylsu...)
Affinity DataIC50:  2.00E+4nMAssay Description:Inhibition of human sEH (1 to 555 residues) expressed in Escherichia coli BL21-(DE3) using PHOME substrate incubated for 30 to 45 mins by fluorescenc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
Columbia University Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM50278145(CHEMBL469546 | N-(2,4-dichlorobenzyl)-1-(mesitylsu...)
Affinity DataIC50:  20nMAssay Description:Inhibition of epoxide hydrolase (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed