BDBM50278715 BAY-414109::CHEMBL605300

SMILES COC(=O)C1=C(C)NC(=N[C@H]1c1ccc(F)cc1Cl)c1ncc(F)cc1F

InChI Key InChIKey=FVNJBPMQWSIGJK-HNNXBMFYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50278715   

TargetCapsid protein(Hepatitis B virus)
Wuxi Apptec (Shanghai)

Curated by ChEMBL
LigandPNGBDBM50278715(BAY-414109 | CHEMBL605300)
Affinity DataIC50:  430nMAssay Description:Inhibition of HBV C150-Bodipy FL N-(2-aminoethyl) maleimide labeled capsid assessed as reduction in NaCl-induced capsid assembly preincubated for 15 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCapsid protein(Hepatitis B virus)
Wuxi Apptec (Shanghai)

Curated by ChEMBL
LigandPNGBDBM50278715(BAY-414109 | CHEMBL605300)
Affinity DataEC50:  48nMAssay Description:Inhibition of hepatitis B virus capsid assembly infected in human HepG2.215 cells assessed as reduction in viral DNA replication measured on day 7 by...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed