BDBM50278724 CHEMBL4169247

SMILES COc1nccnc1NS(=O)(=O)c1cccc(Cl)c1Cl

InChI Key InChIKey=FLSMVCMSUNISFK-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50278724   

TargetC-C chemokine receptor type 4(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50278724(CHEMBL4169247)
Affinity DataIC50:  501nMAssay Description:Antagonist activity at human CCR4 expressed in Th2 cells coexpressing CD45RA+ assessed as inhibition of CCL17 induced chemotaxisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 4(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50278724(CHEMBL4169247)
Affinity DataIC50:  32nMAssay Description:Antagonist activity at human CCR4 expressed in CHO cells coexpressing CD4+ assessed as inhibition of CCL22 induced Ca2+ mobilizationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 4(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50278724(CHEMBL4169247)
Affinity DataIC50:  501nMAssay Description:Antagonist activity at human CCR4 expressed in Th2 cells coexpressing CD45RA+ assessed as inhibition of CCL22 induced chemotaxisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 4(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50278724(CHEMBL4169247)
Affinity DataIC50:  16nMAssay Description:Inhibition of NADH oxidase activity in sub-mitochondrial particles from bovine heartMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 4(Canis lupus familiaris)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50278724(CHEMBL4169247)
Affinity DataIC50:  25nMAssay Description:Inhibition of NADH oxidase activity in sub-mitochondrial particles from bovine heartMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-C chemokine receptor type 4(Mus musculus)
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50278724(CHEMBL4169247)
Affinity DataIC50:  10nMAssay Description:Inhibition of NADH oxidase activity in sub-mitochondrial particles from bovine heartMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed