BDBM50280452 CHEMBL4175845

SMILES C[C@@]1(N=C(N)CO[C@@H]1F)c1cc(NC(=O)c2ncc(cc2F)C#N)ccc1F

InChI Key InChIKey=PASVPQXUHXFXJX-ZWKOTPCHSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50280452   

TargetBeta-secretase 1(Homo sapiens (Human))
Janssen Pharmaceutica

Curated by ChEMBL
LigandPNGBDBM50280452(CHEMBL4175845)
Affinity DataIC50:  18nMAssay Description:In vivo luteinising hormone inhibiting potency in rats is expressed as negative logarithm of the concentration (antagonist)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Janssen Pharmaceutica

Curated by ChEMBL
LigandPNGBDBM50280452(CHEMBL4175845)
Affinity DataIC50:  12nMAssay Description:Inhibition of human WIL2/dihydrofolate reductase activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Janssen Pharmaceutica

Curated by ChEMBL
LigandPNGBDBM50280452(CHEMBL4175845)
Affinity DataIC50: >1.00E+4nMAssay Description:In vivo inhibition of leutenising hormone in rats.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed