BDBM50280473 CHEMBL4169060

SMILES C[C@@]1(N=C(N)CO[C@H]1C(F)(F)F)c1cc(NC(=O)c2ncc(cc2Cl)C#N)ccc1F

InChI Key InChIKey=YXZJAQWZKFLQLN-QZTJIDSGSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50280473   

TargetBeta-secretase 1(Homo sapiens (Human))
Janssen Pharmaceutica

Curated by ChEMBL
LigandPNGBDBM50280473(CHEMBL4169060)
Affinity DataIC50:  29nMAssay Description:Inhibition of L1210 leukemia thymidylate synthase (TS) enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBeta-secretase 1(Homo sapiens (Human))
Janssen Pharmaceutica

Curated by ChEMBL
LigandPNGBDBM50280473(CHEMBL4169060)
Affinity DataIC50:  6.40nMAssay Description:In vivo inhibition of leutenising hormone in rats.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed