BDBM50280870 12-(2,2-difluoroethyl)-13-methyl-6,7,12,13-tetrahydro-5H-indolo[2,3-a]pyrrolo[3,4-c]carbazol-5-one::CHEMBL303990

SMILES Cn1c2ccccc2c2c3C(=O)NCc3c3c4ccccc4n(CC(F)F)c3c12

InChI Key InChIKey=SEAHSSUYMJWMKY-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50280870   

TargetcGMP-dependent protein kinase 1(Bos taurus (bovine))
TBA

Curated by ChEMBL
LigandPNGBDBM50280870(12-(2,2-difluoroethyl)-13-methyl-6,7,12,13-tetrahy...)
Affinity DataIC50:  710nMAssay Description:In vitro for inhibitory activity against cGMP-dependent protein kinase from bovine lung (G-kinase)More data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50280870(12-(2,2-difluoroethyl)-13-methyl-6,7,12,13-tetrahy...)
Affinity DataIC50:  32nMAssay Description:In vitro for inhibitory activity against protein kinase C from rat brainMore data for this Ligand-Target Pair
In DepthDetails Article
TargetMyosin light chain kinase, smooth muscle(Gallus gallus (chicken))
TBA

Curated by ChEMBL
LigandPNGBDBM50280870(12-(2,2-difluoroethyl)-13-methyl-6,7,12,13-tetrahy...)
Affinity DataIC50:  440nMAssay Description:In vitro for inhibitory activity against myosin light-chain kinase from chicken gizzard (M-kinase)More data for this Ligand-Target Pair
In DepthDetails Article
TargetcAMP-dependent protein kinase catalytic subunit alpha(Bos taurus (bovine))
TBA

Curated by ChEMBL
LigandPNGBDBM50280870(12-(2,2-difluoroethyl)-13-methyl-6,7,12,13-tetrahy...)
Affinity DataIC50:  2.40E+3nMAssay Description:In vitro for inhibitory activity against cAMP-dependent protein kinase from bovine heart (A-kinase)More data for this Ligand-Target Pair
In DepthDetails Article