BDBM50286773 CHEMBL4174897
SMILES CC(C)C[C@H](N)C(=O)NS(=O)(=O)c1cccc(NC(=S)NC(=O)COc2ccc(Br)cc2Cl)c1
InChI Key InChIKey=CFBBNKTYQXLBCJ-KRWDZBQOSA-N
Data 2 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 2 hits for monomerid = 50286773
Affinity DataIC50: 4.50E+3nMAssay Description:Inhibition of human cytoplasmic LeuRS assessed as reduction in protein synthesis measured after 10 mins in presence of [3H]Leu by scintillation count...More data for this Ligand-Target Pair
TargetLeucine--tRNA ligase(Trypanosoma brucei brucei (strain 927/4 GUTat10.1))
Oxford Drug Design
Curated by ChEMBL
Oxford Drug Design
Curated by ChEMBL
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of Trypanosoma brucei LeuRS assessed as reduction in protein synthesis pretreated for 20 mins in presence of [14C]Leu followed by ATP addi...More data for this Ligand-Target Pair