BDBM50288547 Acridin-9-yl-(2,2-dimethyl-benzo[1,3]dioxol-5-yl)-acetic acid methyl ester::CHEMBL103572

SMILES COC(=O)C(c1ccc2OC(C)(C)Oc2c1)c1c2ccccc2nc2ccccc12

InChI Key InChIKey=GTLRAUMURPBKNZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50288547   

TargetEndothelin-1 receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50288547(Acridin-9-yl-(2,2-dimethyl-benzo[1,3]dioxol-5-yl)-...)
Affinity DataIC50: >2.50E+4nMAssay Description:Inhibition of binding of [125I]-ET-1 to cloned human Endothelin A receptor expressed in LtK- cellsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetEndothelin-1 receptor(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50288547(Acridin-9-yl-(2,2-dimethyl-benzo[1,3]dioxol-5-yl)-...)
Affinity DataIC50: >2.50E+4nMAssay Description:Antagonistic activity against endothelin A receptor in rabbit renal artery vascular smooth muscle cells.More data for this Ligand-Target Pair
In DepthDetails Article