BDBM50289139 3-((E)-2-Pyridin-2-yl-vinyl)-1H-indole::CHEMBL171548

SMILES C(=C/c1ccccn1)\c1c[nH]c2ccccc12

InChI Key InChIKey=OZPYZRJHDWCCQM-CMDGGOBGSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50289139   

TargetTryptophan 2,3-dioxygenase(Rattus norvegicus)
TBA

Curated by ChEMBL
LigandPNGBDBM50289139(3-((E)-2-Pyridin-2-yl-vinyl)-1H-indole | CHEMBL171...)
Affinity DataKi:  100nMAssay Description:Compound was tested for inhibition of Tryptophan dioxygenase (TDO) from rat liverMore data for this Ligand-Target Pair
In DepthDetails Article
TargetTryptophan 2,3-dioxygenase(Mus musculus)
University Of Namur

Curated by ChEMBL
LigandPNGBDBM50289139(3-((E)-2-Pyridin-2-yl-vinyl)-1H-indole | CHEMBL171...)
Affinity DataIC50:  2.00E+4nMAssay Description:Inhibition of mouse TDO expressed in mouse P815B cells assessed as inhibition of tryptophan catabolism by measuring kynurenine production after 8 hrs...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed