BDBM50289353 2,3-Dibromo-8-(4-methoxy-phenyl)-6H-imidazo[1,2-d][1,2,4]triazin-5-one::CHEMBL426937

SMILES COc1ccc(cc1)-c1n[nH]c(=O)n2c(Br)c(Br)nc12

InChI Key InChIKey=HCLWEXNPZAAMRB-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50289353   

TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50289353(2,3-Dibromo-8-(4-methoxy-phenyl)-6H-imidazo[1,2-d]...)
Affinity DataIC50: >3.00E+4nMAssay Description:In vitro inhibition of phosphodiesterase (PDE V).More data for this Ligand-Target Pair
In DepthDetails Article
LigandPNGBDBM50289353(2,3-Dibromo-8-(4-methoxy-phenyl)-6H-imidazo[1,2-d]...)
Affinity DataIC50:  450nMAssay Description:In vitro inhibition of phosphodiesterase (PDE I).More data for this Ligand-Target Pair
In DepthDetails Article
TargetcGMP-inhibited 3',5'-cyclic phosphodiesterase 3A/3B(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50289353(2,3-Dibromo-8-(4-methoxy-phenyl)-6H-imidazo[1,2-d]...)
Affinity DataIC50:  1.10E+3nMAssay Description:In vitro inhibition of phosphodiesterase (PDE III).More data for this Ligand-Target Pair
In DepthDetails Article