BDBM50289963 CHEMBL3142195::CHEMBL92506::Pentanedioic acid (2R,5R)-5-(6-amino-purin-9-yl)-3,4-diisopropoxy-tetrahydro-furan-2-ylmethyl ester 4-((E)-2-nitro-vinyl)-phenyl ester

SMILES CC(C)O[C@@H]1[C@@H](COC(=O)CCCC(=O)Oc2ccc(\C=C\[N+]([O-])=O)cc2)O[C@H]([C@@H]1OC(C)C)n1cnc2c(N)ncnc12

InChI Key InChIKey=MLTIRIPPEVCTBF-OUKQBFOZSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50289963   

LigandPNGBDBM50289963(CHEMBL3142195 | CHEMBL92506 | Pentanedioic acid (2...)
Affinity DataIC50:  2.00E+3nMAssay Description:Inhibition of ligand-stimulated autophosphorylation of EGFR/HER2 chimeric receptor expressed in NIH3T3 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50289963(CHEMBL3142195 | CHEMBL92506 | Pentanedioic acid (2...)
Affinity DataIC50:  4.50E+3nMAssay Description:Inhibition of autophosphorylation of HER-2 expressed in NIH3T3 cell linesMore data for this Ligand-Target Pair
In DepthDetails Article