BDBM50292680 (1S,2R)-2-cyano-N-hydroxy-2-(4-((2-phenylquinolin-4-yl)methoxy)benzyl)cyclopropanecarboxamide::CHEMBL497769
SMILES ONC(=O)[C@H]1C[C@]1(Cc1ccc(OCc2cc(nc3ccccc23)-c2ccccc2)cc1)C#N
InChI Key InChIKey=PIRLKANLMCDQSE-UFHPHHKVSA-N
Data 7 KI
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 7 hits for monomerid = 50292680
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by ChEMBL
Schering-Plough Research Institute
Curated by ChEMBL
Affinity DataKi: 4nMAssay Description:Inhibition of human recombinant TACEMore data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 10(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by ChEMBL
Schering-Plough Research Institute
Curated by ChEMBL
Affinity DataKi: >1.00E+7nMAssay Description:Inhibition of ADAM10More data for this Ligand-Target Pair
Affinity DataKi: >1.00E+7nMAssay Description:Inhibition of MMP7More data for this Ligand-Target Pair
Target72 kDa type IV collagenase(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by ChEMBL
Schering-Plough Research Institute
Curated by ChEMBL
Affinity DataKi: >1.00E+7nMAssay Description:Inhibition of MMP2More data for this Ligand-Target Pair
TargetInterstitial collagenase(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by ChEMBL
Schering-Plough Research Institute
Curated by ChEMBL
Affinity DataKi: >1.00E+7nMAssay Description:Inhibition of MMP1More data for this Ligand-Target Pair
TargetMatrix metalloproteinase-14(Homo sapiens (Human))
Schering-Plough Research Institute
Curated by ChEMBL
Schering-Plough Research Institute
Curated by ChEMBL
Affinity DataKi: >1.00E+7nMAssay Description:Inhibition of MMP14More data for this Ligand-Target Pair
Affinity DataKi: >1.00E+7nMAssay Description:Inhibition of MMP3More data for this Ligand-Target Pair