BDBM50292746 (+/-)-N-(1-Phenylpropyl)ethanimidamide hydrobromide::CHEMBL450583

SMILES CCC(N=C(C)N)c1ccccc1

InChI Key InChIKey=RSYITLTUUACWQE-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50292746   

TargetNitric oxide synthase, inducible(Homo sapiens (Human))
Universita G. D'Annunzio

Curated by ChEMBL
LigandPNGBDBM50292746((+/-)-N-(1-Phenylpropyl)ethanimidamide hydrobromid...)
Affinity DataIC50:  250nMAssay Description:Inhibition of iNOS in LPS treated human THP1 cell homogenate assessed as conversion of L-[2,3-3H]arginine to L-[2,3-3H]citrulline preincubated 1 hr b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, endothelial(Homo sapiens (Human))
Universita G. D'Annunzio

Curated by ChEMBL
LigandPNGBDBM50292746((+/-)-N-(1-Phenylpropyl)ethanimidamide hydrobromid...)
Affinity DataIC50:  8.00E+4nMAssay Description:Inhibition of eNOS in LPS treated human THP1 cell homogenate assessed as conversion of L-[2,3-3H]arginine to L-[2,3-3H]citrulline preincubated 1 hr b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, inducible(Mus musculus (mouse))
Università

Curated by ChEMBL
LigandPNGBDBM50292746((+/-)-N-(1-Phenylpropyl)ethanimidamide hydrobromid...)
Affinity DataIC50:  250nMAssay Description:Inhibition of mouse macrophage iNOS assessed as nitric oxide mediated oxidation of oxyhemoglobin to methemoglobinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, brain(Rattus norvegicus (rat))
Università

Curated by ChEMBL
LigandPNGBDBM50292746((+/-)-N-(1-Phenylpropyl)ethanimidamide hydrobromid...)
Affinity DataIC50:  9.00E+4nMAssay Description:Inhibition of rat brain nNOS assessed as nitric oxide mediated oxidation of oxyhemoglobin to methemoglobinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNitric oxide synthase, endothelial(Bos taurus (bovine))
Università

Curated by ChEMBL
LigandPNGBDBM50292746((+/-)-N-(1-Phenylpropyl)ethanimidamide hydrobromid...)
Affinity DataIC50:  8.00E+4nMAssay Description:Inhibition of bovine eNOS assessed as nitric oxide mediated oxidation of oxyhemoglobin to methemoglobinMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed