BDBM50293245 CHEMBL496968::N,N'-(5-(4-(5-chlorobenzo[d][1,3]dioxol-4-ylamino)pyrimidin-2-ylamino)-1,3-phenylene)dimethanesulfonamide

SMILES CS(=O)(=O)Nc1cc(Nc2nccc(Nc3c4OCOc4ccc3Cl)n2)cc(NS(C)(=O)=O)c1

InChI Key InChIKey=PUNOHVAFQIIDRY-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50293245   

TargetEphrin type-B receptor 4(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50293245(CHEMBL496968 | N,N'-(5-(4-(5-chlorobenzo[d][1,3]di...)
Affinity DataIC50:  7.18E+3nMAssay Description:Inhibition of Myc-His-tagged EphB4 expressed in CHOK1 cells assessed as phosphorylation by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEphrin type-B receptor 4(Homo sapiens (Human))
Astrazeneca

Curated by ChEMBL
LigandPNGBDBM50293245(CHEMBL496968 | N,N'-(5-(4-(5-chlorobenzo[d][1,3]di...)
Affinity DataIC50:  15nMAssay Description:Inhibition of EphB4More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed