BDBM50293256 CHEMBL497184::N-(3-chloro-4-(3-fluorobenzyloxy)phenyl)-6-(((2S,4R)-4-ethoxypyrrolidin-2-yl)ethynyl)thieno[3,2-d]pyrimidin-4-amine

SMILES CCO[C@H]1CN[C@@H](C1)C#Cc1cc2ncnc(Nc3ccc(OCc4cccc(F)c4)c(Cl)c3)c2s1

InChI Key InChIKey=SFLDOYMGTGAPKO-TZIWHRDSSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50293256   

TargetReceptor tyrosine-protein kinase erbB-2(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50293256(CHEMBL497184 | N-(3-chloro-4-(3-fluorobenzyloxy)ph...)
Affinity DataIC50:  98nMAssay Description:Inhibition of ErbB2 kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEpidermal growth factor receptor(Homo sapiens (Human))
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50293256(CHEMBL497184 | N-(3-chloro-4-(3-fluorobenzyloxy)ph...)
Affinity DataIC50:  115nMAssay Description:Inhibition of EGFR kinaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed