BDBM50293789 3-endo-(Pyridin-2-ylsulfonyl)-N-[4-(trifluoromethyl)phenyl]-8-azabicyclo[3.2.1]octane-8-carboxamide::CHEMBL549545

SMILES FC(F)(F)c1ccc(NC(=O)N2[C@@H]3CC[C@@H]2CC(C3)S(=O)(=O)c2ccccn2)cc1

InChI Key InChIKey=WYCGDOXAJCYGEC-HZPDHXFCSA-N

Data  9 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 9 hits for monomerid = 50293789   

TargetElongation of very long chain fatty acids protein 6(Mus musculus)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50293789(3-endo-(Pyridin-2-ylsulfonyl)-N-[4-(trifluoromethy...)
Affinity DataIC50:  30nMAssay Description:Inhibition of ELOVL6 in mouse H2.35 cells assessed as reduction in elongation index using [14C]palmitic acid as radiotracer after 4 hrs by radio-HPLC...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetElongation of very long chain fatty acids protein 6(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50293789(3-endo-(Pyridin-2-ylsulfonyl)-N-[4-(trifluoromethy...)
Affinity DataIC50:  79nMAssay Description:Inhibition of human ELOVL6 expressed in Pichia pastoris SND1168More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetElongation of very long chain fatty acids protein 6(Mus musculus)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50293789(3-endo-(Pyridin-2-ylsulfonyl)-N-[4-(trifluoromethy...)
Affinity DataIC50:  94nMAssay Description:Inhibition of mouse ELOVL6 expressed in Pichia pastoris SND1168More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetElongation of very long chain fatty acids protein 3(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50293789(3-endo-(Pyridin-2-ylsulfonyl)-N-[4-(trifluoromethy...)
Affinity DataIC50:  6.94E+3nMAssay Description:Inhibition of human ELOVL3 expressed in Pichia pastoris SND1168More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetElongation of very long chain fatty acids protein 5(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50293789(3-endo-(Pyridin-2-ylsulfonyl)-N-[4-(trifluoromethy...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human ELOVL5 expressed in Pichia pastoris SND1168More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetElongation of very long chain fatty acids protein 3(Mus musculus)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50293789(3-endo-(Pyridin-2-ylsulfonyl)-N-[4-(trifluoromethy...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of mouse ELOVL3 expressed in Pichia pastoris SND1168More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetElongation of very long chain fatty acids protein 1(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50293789(3-endo-(Pyridin-2-ylsulfonyl)-N-[4-(trifluoromethy...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human ELOVL1 expressed in Pichia pastoris SND1168More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetElongation of very long chain fatty acids protein 2(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50293789(3-endo-(Pyridin-2-ylsulfonyl)-N-[4-(trifluoromethy...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human ELOVL2 expressed in Pichia pastoris SND1168More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50293789(3-endo-(Pyridin-2-ylsulfonyl)-N-[4-(trifluoromethy...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human ERG channelMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed