BDBM50294034 (R,S)-2-(3,3-Diethylthioureido)-4-methyl-4,5,6,7-tetrahydrobenzo[b]thiophene-3-carboxylic Acid::CHEMBL551696

SMILES CCN(CC)C(=S)Nc1sc2CCCC(C)c2c1C(O)=O

InChI Key InChIKey=NSEWXOVGFYEDFR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50294034   

TargetBroad substrate specificity ATP-binding cassette transporter ABCG2(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50294034((R,S)-2-(3,3-Diethylthioureido)-4-methyl-4,5,6,7-t...)
Affinity DataIC50:  9.10E+3nMAssay Description:Inhibition of BCRP expressed in MCF7 MX cells by Hoechst 33342 stainingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMultidrug resistance-associated protein 1(Homo sapiens (Human))
University Of Bonn

Curated by ChEMBL
LigandPNGBDBM50294034((R,S)-2-(3,3-Diethylthioureido)-4-methyl-4,5,6,7-t...)
Affinity DataIC50:  4.06E+3nMAssay Description:Inhibition of MRP1 expressed in multidrug resistant human 2008 cells assessed as calcein AM accumulation by fluorescence assay in presence of p-gp an...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed