BDBM50296073 CHEMBL562883::sodium(3R,5S,E)-7-(4-(3-(4-fluorophenyl)pentan-3-yl)-2-isopropylphenyl)-3,5-dihydroxyhept-6-enoate

SMILES CCC(CC)(c1ccc(F)cc1)c1ccc(\C=C\[C@@H](O)C[C@@H](O)CC([O-])=O)c(c1)C(C)C

InChI Key InChIKey=PRTAAFRMQSHVEO-GZYSQLKFSA-M

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50296073   

Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
The University Of Tokyo

Curated by ChEMBL
LigandPNGBDBM50296073(CHEMBL562883 | sodium(3R,5S,E)-7-(4-(3-(4-fluoroph...)
Affinity DataIC50:  2.20E+3nMAssay Description:Inhibition of rat HMG-CoA reductase using 0.37 MBq DL-[3-14C]HMG-CoAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target3-hydroxy-3-methylglutaryl-coenzyme A reductase(Rattus norvegicus (rat))
The University Of Tokyo

Curated by ChEMBL
LigandPNGBDBM50296073(CHEMBL562883 | sodium(3R,5S,E)-7-(4-(3-(4-fluoroph...)
Affinity DataIC50:  2.60E+4nMAssay Description:Inhibition of rat HMG-CoA reductase using 3.7 MBq DL-[3-14C]HMG-CoAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed