BDBM50296249 (1R,2S,3S,5S)-methyl 8-(4-fluorobut-2-ynyl)-3-p-tolyl-8-azabicyclo[3.2.1]octane-2-carboxylate::CHEMBL562115
SMILES COC(=O)[C@@H]1[C@H]2CC[C@@H](C[C@@H]1c1ccc(C)cc1)N2CC#CCF
InChI Key InChIKey=UTLIGDFWNZZYCH-MANSERQUSA-N
Data 7 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 7 hits for monomerid = 50296249
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Brookhaven National Laboratory
Curated by ChEMBL
Brookhaven National Laboratory
Curated by ChEMBL
Affinity DataIC50: 3nMAssay Description:Inhibition of human dopamine transporterMore data for this Ligand-Target Pair
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Johannes Gutenberg University
Curated by ChEMBL
Johannes Gutenberg University
Curated by ChEMBL
Affinity DataIC50: 22.5nMAssay Description:Displacement of [3H]nisoxetine from human NET expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Johannes Gutenberg University
Curated by ChEMBL
Johannes Gutenberg University
Curated by ChEMBL
Affinity DataIC50: 31.0nMAssay Description:Displacement of [3H]NE from human NET expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Brookhaven National Laboratory
Curated by ChEMBL
Brookhaven National Laboratory
Curated by ChEMBL
Affinity DataIC50: 3.26nMAssay Description:Displacement of [3H]DA from human DAT expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Johannes Gutenberg University
Curated by ChEMBL
Johannes Gutenberg University
Curated by ChEMBL
Affinity DataIC50: 240nMAssay Description:Displacement of [3H]5-HT from human SERT expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Brookhaven National Laboratory
Curated by ChEMBL
Brookhaven National Laboratory
Curated by ChEMBL
Affinity DataIC50: 1.93nMAssay Description:Displacement of [3H]WIN35,428 from human DAT expressed in HEK293 cellsMore data for this Ligand-Target Pair
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Johannes Gutenberg University
Curated by ChEMBL
Johannes Gutenberg University
Curated by ChEMBL
Affinity DataIC50: 108nMAssay Description:Displacement of [3H]citalopram from human SERT expressed in HEK293 cellsMore data for this Ligand-Target Pair