BDBM50296297 3-(2-hydroxyethoxy)-4-methoxy-N-(5-(3-(trifluoromethyl)benzyl)thiophen-2-yl)benzamide::CHEMBL563632

SMILES COc1ccc(cc1OCCO)C(=O)Nc1ccc(Cc2cccc(c2)C(F)(F)F)s1

InChI Key InChIKey=RWLJEWOYURWKLV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50296297   

TargetStearoyl-CoA desaturase(Homo sapiens (Human))
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50296297(3-(2-hydroxyethoxy)-4-methoxy-N-(5-(3-(trifluorome...)
Affinity DataIC50:  145nMAssay Description:Inhibition of stearoyl-CoA desaturase 1 in human microsome assessed as conversion of [14C]stearate to [14C]oleateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAcyl-CoA desaturase 1(Mus musculus)
Daiichi Sankyo

Curated by ChEMBL
LigandPNGBDBM50296297(3-(2-hydroxyethoxy)-4-methoxy-N-(5-(3-(trifluorome...)
Affinity DataIC50:  76nMAssay Description:Inhibition of stearoyl-CoA desaturase 1 in mouse microsome assessed as conversion of [14C]stearate to [14C]oleateMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed