BDBM50297264 5-Fluoro-3-[2-(5-fluoro-3a,7a-dihydro-indol-1-yl)-ethyl]-1H-indole::CHEMBL563948

SMILES Fc1ccc2n(CCc3c[nH]c4ccc(F)cc34)ccc2c1

InChI Key InChIKey=IATLPOGHDMIAKD-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50297264   

TargetCyclin-dependent kinase 4(Homo sapiens (Human))
University Of Leicester

Curated by ChEMBL
LigandPNGBDBM50297264(5-Fluoro-3-[2-(5-fluoro-3a,7a-dihydro-indol-1-yl)-...)
Affinity DataIC50:  7.30E+4nMAssay Description:Inhibition of human CDK4/ Cyclin D1 catalytic subunit expressed in Sf9 insect cells assessed as GST-RB152 fusion protein phosphorylation-associated d...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 2(Homo sapiens (Human))
University Of Leicester

Curated by ChEMBL
LigandPNGBDBM50297264(5-Fluoro-3-[2-(5-fluoro-3a,7a-dihydro-indol-1-yl)-...)
Affinity DataIC50:  8.95E+5nMAssay Description:Inhibition of human CDK2/ Cyclin A catalytic subunit expressed in Sf9 insect cells assessed as histone H1 phosphorylation-associated depletion in ATP...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed