BDBM50297374 3-(3-(tert-butylthio)-5-(pyridin-2-ylmethoxy)-1-(4-(pyridin-3-yl)benzyl)-1H-indol-2-yl)-2,2-dimethylpropanoic acid::CHEMBL538632
SMILES CC(C)(C)Sc1c(CC(C)(C)C(O)=O)n(Cc2ccc(cc2)-c2cccnc2)c2ccc(OCc3ccccn3)cc12
InChI Key InChIKey=JLCRPHKUMRKGFQ-UHFFFAOYSA-N
Data 4 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 4 hits for monomerid = 50297374
TargetArachidonate 5-lipoxygenase-activating protein(Homo sapiens (Human))
Amira Pharmaceuticals
Curated by ChEMBL
Amira Pharmaceuticals
Curated by ChEMBL
Affinity DataIC50: 9nMAssay Description:Displacement of [3H]3-[5-(pyrid-2-ylmethoxy)-3-tert-butylthio-1-benzyl-indol-2-yl]-2,2-dimethylpropionic acid from FLAP in human polymorphonuclear ce...More data for this Ligand-Target Pair
Affinity DataIC50: 4.70nMAssay Description:Inhibition of CYP3A4More data for this Ligand-Target Pair
Affinity DataIC50: 2.60nMAssay Description:Inhibition of CYP2D6More data for this Ligand-Target Pair