BDBM50297741 (R)-5-cyano-3-(3,4-dioxo-2-(1-(thiophen-2-yl)propylamino)cyclobut-1-enylamino)-2-hydroxy-N,N-dimethylbenzamide::CHEMBL563875

SMILES CC[C@@H](Nc1c(Nc2cc(cc(C(=O)N(C)C)c2O)C#N)c(=O)c1=O)c1cccs1

InChI Key InChIKey=VBCZYGZLNUHVPO-CYBMUJFWSA-N

Data  2 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50297741   

TargetC-X-C chemokine receptor type 2(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50297741((R)-5-cyano-3-(3,4-dioxo-2-(1-(thiophen-2-yl)propy...)
Affinity DataKi:  5nMAssay Description:Displacement of human [125I]IL-8 from human CXCR2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetC-X-C chemokine receptor type 1(Homo sapiens (Human))
Schering-Plough Research Institute

Curated by ChEMBL
LigandPNGBDBM50297741((R)-5-cyano-3-(3,4-dioxo-2-(1-(thiophen-2-yl)propy...)
Affinity DataKi:  54nMAssay Description:Displacement of human [125I]IL-8 from human CXCR1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed