BDBM50299053 CHEMBL573714::N-Hydroxy-2-(2-(4-methoxyphenylsulfonyl)phenyl)acetamide
SMILES COc1ccc(cc1)S(=O)(=O)c1ccccc1CC(=O)NO
InChI Key InChIKey=ITWGWXCEGHFMHT-UHFFFAOYSA-N
Data 15 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 15 hits for monomerid = 50299053
Affinity DataIC50: 98nMAssay Description:Inhibition of para-aminophenylmercuric acetate-activated human recombinant pro-MMP9 catalytic domain after 4 hrs by fluorimetryMore data for this Ligand-Target Pair
Affinity DataIC50: 4.10E+3nMAssay Description:Inhibition of para-aminophenylmercuric acetate-activated human pro-MMP1 after 4 hrs by fluorimetryMore data for this Ligand-Target Pair
Affinity DataIC50: 98nMAssay Description:Inhibition of recombinant human MMP9 after 2 hrs using FS-6 as substrate by fluorometryMore data for this Ligand-Target Pair
Target72 kDa type IV collagenase(Homo sapiens (Human))
Uit The Arctic University Of Norway
Curated by ChEMBL
Uit The Arctic University Of Norway
Curated by ChEMBL
Affinity DataIC50: 230nMAssay Description:Inhibition of recombinant human MMP2 after 2 hrs using FS-6 as substrate by fluorometryMore data for this Ligand-Target Pair
Affinity DataIC50: 1.70E+4nMAssay Description:Inhibition of Bacillus thermoproteolyticus pseudolysin pretreated with compound for 15 mins followed by the addition of Abz-Ala-Gly-leu-Ala-p-nitrobe...More data for this Ligand-Target Pair
Affinity DataIC50: 2.90E+4nMAssay Description:Inhibition of Pseudomonas aeruginosa pseudolysin pretreated with compound for 1 hr followed by the addition of 1.73 uM bradykinin like substrate by s...More data for this Ligand-Target Pair
Affinity DataIC50: 1.46E+5nMAssay Description:Inhibition of Bacillus thermoproteolyticus thermolysin pretreated with compound for 1 hr followed by the addition of 3.33 uM bradykinin like substrat...More data for this Ligand-Target Pair
TargetDisintegrin and metalloproteinase domain-containing protein 17(Homo sapiens (Human))
Uit The Arctic University Of Norway
Curated by ChEMBL
Uit The Arctic University Of Norway
Curated by ChEMBL
Affinity DataIC50: 6.70E+4nMAssay Description:Inhibition of recombinant human ADAM17 after 30 mins using FS-6 as substrate by fluorometryMore data for this Ligand-Target Pair
Affinity DataIC50: 32nMAssay Description:Inhibition of autoactivated human pro-MMP12 after 4 hrs by fluorimetryMore data for this Ligand-Target Pair
Affinity DataIC50: 84nMAssay Description:Inhibition of para-aminophenylmercuric acetate-activated human pro-MMP13 after 4 hrs by fluorimetryMore data for this Ligand-Target Pair
Affinity DataIC50: 130nMAssay Description:Inhibition of human recombinant pro-MMP16 catalytic domain after 4 hrs by fluorimetryMore data for this Ligand-Target Pair
Target72 kDa type IV collagenase(Homo sapiens (Human))
Uit The Arctic University Of Norway
Curated by ChEMBL
Uit The Arctic University Of Norway
Curated by ChEMBL
Affinity DataIC50: 230nMAssay Description:Inhibition of para-aminophenylmercuric acetate-activated human recombinant pro-MMP2 catalytic domain after 4 hrs by fluorimetryMore data for this Ligand-Target Pair
Affinity DataIC50: 280nMAssay Description:Inhibition of para-aminophenylmercuric acetate-activated human pro-MMP8 after 4 hrs by fluorimetryMore data for this Ligand-Target Pair
Affinity DataIC50: 730nMAssay Description:Inhibition of trypsin activated human pro-MMP3 after 4 hrs by fluorimetryMore data for this Ligand-Target Pair
Affinity DataIC50: 200nMAssay Description:Inhibition of human recombinant pro-MMP14 catalytic domain after 4 hrs by fluorimetryMore data for this Ligand-Target Pair