BDBM50299778 CHEMBL574870::N-(4-(6,7-dimethoxyquinazolin-4-yloxy)-3-fluorophenyl)-2-oxo-3-phenylimidazolidine-1-carboxamide

SMILES COc1cc2ncnc(Oc3ccc(NC(=O)N4CCN(C4=O)c4ccccc4)cc3F)c2cc1OC

InChI Key InChIKey=UPLHEVGVTBVSLK-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50299778   

TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50299778(CHEMBL574870 | N-(4-(6,7-dimethoxyquinazolin-4-ylo...)
Affinity DataIC50:  40nMAssay Description:Inhibition of GST-tagged c-Met expressed in Sf9 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHepatocyte growth factor receptor(Homo sapiens (Human))
Methylgene

Curated by ChEMBL
LigandPNGBDBM50299778(CHEMBL574870 | N-(4-(6,7-dimethoxyquinazolin-4-ylo...)
Affinity DataIC50: >1.00E+3nMAssay Description:Inhibition of TPR-Met assessed as autophosphorylationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed