BDBM50299869 CHEMBL577030::ethyl 2-methyl-6-oxo-5-(2-(pyridin-4-yl)thiazol-4-yl)-1,6-dihydropyridine-3-carboxylate

SMILES CCOC(=O)c1cc(-c2csc(n2)-c2ccncc2)c(=O)[nH]c1C

InChI Key InChIKey=MUDAPTILNSVOOR-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50299869   

TargetCyclin-dependent kinase 5 activator 1(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50299869(CHEMBL577030 | ethyl 2-methyl-6-oxo-5-(2-(pyridin-...)
Affinity DataIC50:  131nMAssay Description:Inhibition of human CDK5/p25 assessed as histone h1 phosphorylation in presence of ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCyclin-dependent kinase 5(Homo sapiens (Human))
Amgen

Curated by ChEMBL
LigandPNGBDBM50299869(CHEMBL577030 | ethyl 2-methyl-6-oxo-5-(2-(pyridin-...)
Affinity DataIC50:  131nMAssay Description:Inhibition of human CDK5More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed