BDBM50299946 1-{[(-)-6-Chloro-2-oxo-4-(trifluoromethyl)-1,4-dihydro-2H-3,1-benzoxazin-4-yl]methyl}-3-(4-fluorophenyl)urea::1-{[6-Chloro-2-oxo-4-(trifluoromethyl)-1,4-dihydro-2H-3,1-benzoxazin-4-yl]methyl}-3-(4-fluorophenyl)urea::CHEMBL570576

SMILES Fc1ccc(NC(=O)NCC2(OC(=O)Nc3ccc(Cl)cc23)C(F)(F)F)cc1

InChI Key InChIKey=BJJLMCGAKMRHBT-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50299946   

TargetElongation of very long chain fatty acids protein 6(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50299946(1-{[(-)-6-Chloro-2-oxo-4-(trifluoromethyl)-1,4-dih...)
Affinity DataIC50:  33nMAssay Description:Inhibition of human ELOVL6 expressed in Pichia pastoris using palmitoyl-CoA by long chain fatty acyl-CoA elongation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetElongation of very long chain fatty acids protein 6(Mus musculus)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50299946(1-{[(-)-6-Chloro-2-oxo-4-(trifluoromethyl)-1,4-dih...)
Affinity DataIC50:  377nMAssay Description:Inhibition of ELOVL6 in mouse H2.35 cells assessed as elongation indexMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetElongation of very long chain fatty acids protein 6(Mus musculus)
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50299946(1-{[(-)-6-Chloro-2-oxo-4-(trifluoromethyl)-1,4-dih...)
Affinity DataIC50:  31nMAssay Description:Inhibition of mouse ELOVL6 expressed in Pichia pastoris using palmitoyl-CoA by long chain fatty acyl-CoA elongation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetElongation of very long chain fatty acids protein 6(Homo sapiens (Human))
Tsukuba Research Institute

Curated by ChEMBL
LigandPNGBDBM50299946(1-{[(-)-6-Chloro-2-oxo-4-(trifluoromethyl)-1,4-dih...)
Affinity DataIC50:  33nMAssay Description:Inhibition of human ELOVL6 expressed in Pichia pastoris using palmitoyl-CoA by long chain fatty acyl-CoA elongation assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed