BDBM50299980 (R)-1-(Methylsulfonylamino)-3-[2-(4-methoxyphenyl)ethyl]-4-(4-methoxy-phenyl)-2-imidazolidinone::CHEMBL569185
SMILES COc1ccc(CCN2[C@@H](CN(NS(C)(=O)=O)C2=O)c2ccc(OC)cc2)cc1
InChI Key InChIKey=GFFIHDXPUGXVGG-IBGZPJMESA-N
Data 11 IC50
Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB
Found 11 hits for monomerid = 50299980
TargetVoltage-dependent L-type calcium channel subunit alpha-1C(Homo sapiens (Human))
Wyeth Research
Curated by ChEMBL
Wyeth Research
Curated by ChEMBL
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of Cav1.2 expressed in CHO cells by patch-clamp techniqueMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily A member 5(Homo sapiens (Human))
Wyeth Research
Curated by ChEMBL
Wyeth Research
Curated by ChEMBL
Affinity DataIC50: 480nMAssay Description:Inhibition of human Kv1.5 expressed in CHO cells by patch-clamp techniqueMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily H member 2(Homo sapiens (Human))
Wyeth Research
Curated by ChEMBL
Wyeth Research
Curated by ChEMBL
Affinity DataIC50: 1.51E+4nMAssay Description:Inhibition of human ERG by patch-clamp techniqueMore data for this Ligand-Target Pair
TargetSodium channel protein type 5 subunit alpha(Homo sapiens (Human))
Wyeth Research
Curated by ChEMBL
Wyeth Research
Curated by ChEMBL
Affinity DataIC50: >3.00E+4nMAssay Description:Inhibition of Nav1.5 expressed in CHO cells by patch-clamp techniqueMore data for this Ligand-Target Pair
TargetVoltage-dependent L-type calcium channel subunit alpha-1D(Homo sapiens (Human))
Wyeth Research
Curated by ChEMBL
Wyeth Research
Curated by ChEMBL
Affinity DataIC50: 2.34E+4nMAssay Description:Inhibition of Cav1.3 expressed in CHO cells by patch-clamp techniqueMore data for this Ligand-Target Pair
Affinity DataIC50: 4.70E+4nMAssay Description:Inhibition of CYP2C9 in human liver microsomesMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily A member 3(Homo sapiens (Human))
Wyeth Research
Curated by ChEMBL
Wyeth Research
Curated by ChEMBL
Affinity DataIC50: 1.41E+3nMAssay Description:Inhibition of Kv1.3 expressed in CHO cells by patch-clamp techniqueMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily D member 3(Homo sapiens (Human))
Wyeth Research
Curated by ChEMBL
Wyeth Research
Curated by ChEMBL
Affinity DataIC50: 3.87E+3nMAssay Description:Inhibition of Kv4.3 expressed in CHO cells by patch-clamp techniqueMore data for this Ligand-Target Pair
Affinity DataIC50: 3.70E+4nMAssay Description:Inhibition of CYP3A4 in human liver microsomesMore data for this Ligand-Target Pair
Affinity DataIC50: 1.80E+5nMAssay Description:Inhibition of CYP2D6 in human liver microsomesMore data for this Ligand-Target Pair
TargetPotassium voltage-gated channel subfamily A member 1(Homo sapiens (Human))
Wyeth Research
Curated by ChEMBL
Wyeth Research
Curated by ChEMBL
Affinity DataIC50: 2.66E+3nMAssay Description:Inhibition of Kv1.1 expressed in CHO cells by patch-clamp techniqueMore data for this Ligand-Target Pair