BDBM50300671 2-(5-{[(6-Chloroimidazo[2,1-b][1,3]thiazol-5-yl)sulfonyl]amino}-2,3-dihydro-1H-inden-1-ylidene)hydrazinecarboximidamide hydrochloride::CHEMBL578631

SMILES NC(=N)N\N=C1/CCc2cc(NS(=O)(=O)c3c(Cl)nc4sccn34)ccc12

InChI Key InChIKey=APZPEQGMHIRRFU-RGVLZGJSSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50300671   

Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Universitat De Barcelona

Curated by ChEMBL
LigandPNGBDBM50300671(2-(5-{[(6-Chloroimidazo[2,1-b][1,3]thiazol-5-yl)su...)
Affinity DataKi:  2.60nMAssay Description:Displacement of [3H]LSD from human recombinant 5HT6 receptor expressed in HEK293 cells after 60 mins by liquid scintillation countingMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Homo sapiens (Human))
Universitat De Barcelona

Curated by ChEMBL
LigandPNGBDBM50300671(2-(5-{[(6-Chloroimidazo[2,1-b][1,3]thiazol-5-yl)su...)
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of human 5HT1A receptorMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 6(Homo sapiens (Human))
Universitat De Barcelona

Curated by ChEMBL
LigandPNGBDBM50300671(2-(5-{[(6-Chloroimidazo[2,1-b][1,3]thiazol-5-yl)su...)
Affinity DataIC50:  47nMAssay Description:Antagonist activity at human 5HT6 receptor expressed in HEK293F cells assessed as inhibition of 5HT-stimulated cAMP production after 30 mins by HTRF ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed