BindingDB BDBM50300690 1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morpholin-4-Yl)ethoxy]imidazo[2,1-B][1,3]benzothiazol-2-Yl}phenyl)urea::AC 010220::AC 220::AC-220::AC010220::AC220::ASP-2689::CHEMBL576982::N-(5-tert-Butyl-isoxazol-3-yl)-N'-{4-[7-(2-morpholin-4-yl-ethoxy)imidazo[2,1-b][1,3]benzothiazol-2-yl]phenyl}urea::Quizartinib::Quizartinib (AC220)::US10266535, Compound AC220::US11542261, Compound quizartinib::US9216997, Quizartinib (positive compound)

BDBM50300690 1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morpholin-4-Yl)ethoxy]imidazo[2,1-B][1,3]benzothiazol-2-Yl}phenyl)urea::AC 010220::AC 220::AC-220::AC010220::AC220::ASP-2689::CHEMBL576982::N-(5-tert-Butyl-isoxazol-3-yl)-N'-{4-[7-(2-morpholin-4-yl-ethoxy)imidazo[2,1-b][1,3]benzothiazol-2-yl]phenyl}urea::Quizartinib::Quizartinib (AC220)::US10266535, Compound AC220::US11542261, Compound quizartinib::US9216997, Quizartinib (positive compound)

SMILES CC(C)(C)c1cc(NC(=O)Nc2ccc(cc2)-c2cn3c(n2)sc2cc(OCCN4CCOCC4)ccc32)no1

InChI Key InChIKey=CVWXJKQAOSCOAB-UHFFFAOYSA-N

Data 83 IC50 857 Kd

PDB links: 2 PDB IDs match this monomer.

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50300690

Vascular endothelial growth factor receptor 2(Homo sapiens (Human))
National Health Research Institutes

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

IC50: 430nMAssay Description:Inhibition of recombinant GST-tagged VEGFR2 kinase domain (V789 to V1356) (unknown origin) expressed in insect Sf9 cells using polyGlu4:Tyr peptide a...More data for this Ligand-Target Pair

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Receptor-type tyrosine-protein kinase FLT3(Homo sapiens (Human))
National Health Research Institutes

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

IC50: 69nMAssay Description:Inhibition of wild type GST-tagged FLT3 kinase domain (Y567 to S993) (unknown origin) expressed in baculovirus infected insect Sf9 cells using Her2 p...More data for this Ligand-Target Pair

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Aurora kinase A(Homo sapiens (Human))
National Health Research Institutes

Curated by ChEMBL

BDBM50300690(1-(5-Tert-Butyl-1,2-Oxazol-3-Yl)-3-(4-{7-[2-(Morph...)

IC50: >1.00E+4nMAssay Description:Inhibition of recombinant GST-tagged Aurora-A kinase domain (S123 to S401) (unknown origin) expressed in insect Sf9 cells using tetra(LRRASLG) peptid...More data for this Ligand-Target Pair

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Filter my 940 hits

Targets 392▿
- Receptor-type tyrosine-protein kinase FLT3 75
- Tyrosine-protein kinase ABL1 16
- Mast/stem cell growth factor receptor Kit 13
- Epidermal growth factor receptor 13
- Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform 11
- Proto-oncogene tyrosine-protein kinase receptor Ret 11
- Platelet-derived growth factor receptor beta 8
- Platelet-derived growth factor receptor alpha 8
- Macrophage colony-stimulating factor 1 receptor 6
- Vascular endothelial growth factor receptor 2 6
- Interleukin-1 receptor-associated kinase 1 5
- Aurora kinase A 5
- Vascular endothelial growth factor receptor 3 5
- Vascular endothelial growth factor receptor 1 5
- Interleukin-1 receptor-associated kinase 4 4
- Tyrosine-protein kinase Lck 4
- Ephrin type-A receptor 6 4
- Tyrosine-protein kinase JAK1 4
- Ribosomal protein S6 kinase alpha-6 4
- Tyrosine-protein kinase Blk 4
- Ribosomal protein S6 kinase alpha-4 4
- Ribosomal protein S6 kinase alpha-5 4
- Ribosomal protein S6 kinase alpha-2 4
- Ribosomal protein S6 kinase alpha-1 4
- SRSF protein kinase 1 4
- Hepatocyte growth factor receptor 4
- Epithelial discoidin domain-containing receptor 1 4
- Non-receptor tyrosine-protein kinase TYK2 4
- Mitogen-activated protein kinase 14 4
- Cyclin-dependent kinase 2 3
- Discoidin domain-containing receptor 2 3
- Dimer of Receptor-type tyrosine-protein kinase FLT3 3
- Cyclin-H/Cyclin-dependent kinase 7 3
- Myosin light chain kinase, smooth muscle 3
- Serine/threonine-protein kinase B-raf 3
- Receptor-interacting serine/threonine-protein kinase 1 3
- Serine/threonine-protein kinase TAO1 3
- Calcium/calmodulin-dependent protein kinase type II subunit gamma 3
- Receptor-type tyrosine-protein kinase FLT3 [D835Y] 3
- Fibroblast growth factor receptor 3 3
- Tyrosine-protein kinase Tec 2
- BMP-2-inducible protein kinase 2
- Rhodopsin kinase GRK1 2
- Cyclin-dependent kinase 11B 2
- Cyclin-dependent kinase 11A 2
- Uncharacterized serine/threonine-protein kinase SBK3 2
- LIM domain kinase 1 2
- LIM domain kinase 2 2
- ALK tyrosine kinase receptor 2
- NUAK family SNF1-like kinase 2 2
- Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform 2
- Glycogen synthase kinase-3 beta 2
- Calcium/calmodulin-dependent protein kinase type 1 2
- NUAK family SNF1-like kinase 1 2
- Calcium/calmodulin-dependent protein kinase type II subunit beta 2
- AP2-associated protein kinase 1 2
- Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform 2
- Serine/threonine-protein kinase PAK 1 2
- Protein kinase C theta type 2
- Serine/threonine-protein kinase PAK 2 2
- Serine/threonine-protein kinase PAK 3 2
- Dual specificity mitogen-activated protein kinase kinase 2 2
- Serine/threonine-protein kinase PAK 4 2
- Phosphatidylinositol 5-phosphate 4-kinase type-2 beta 2
- Serine/threonine-protein kinase tousled-like 2 2
- Dual specificity mitogen-activated protein kinase kinase 3 2
- Serine/threonine-protein kinase PAK 5 2
- Serine/threonine-protein kinase PAK 6 2
- Serine/threonine-protein kinase tousled-like 1 2
- Tyrosine-protein kinase JAK3 2
- Tyrosine-protein kinase JAK2 2
- Dual specificity mitogen-activated protein kinase kinase 1 2
- Dual specificity mitogen-activated protein kinase kinase 6 2
- Dual specificity mitogen-activated protein kinase kinase 4 2
- Leucine-rich repeat serine/threonine-protein kinase 2 2
- Tyrosine-protein kinase ZAP-70 2
- Casein kinase I isoform gamma-3 2
- Casein kinase I isoform gamma-2 2
- Casein kinase I isoform epsilon 2
- Casein kinase I isoform gamma-1 2
- Ephrin type-A receptor 1 2
- Ephrin type-A receptor 3 2
- Ephrin type-A receptor 2 2
- Ephrin type-A receptor 5 2
- Tyrosine-protein kinase BTK 2
- Ephrin type-A receptor 4 2
- Tyrosine-protein kinase receptor UFO 2
- Insulin-like growth factor 1 receptor 2
- Activin receptor type-1 2
- Myosin light chain kinase 2, skeletal/cardiac muscle 2
- Tyrosine-protein kinase Srms 2
- Wee1-like protein kinase 2
- Serine/threonine-protein kinase MAK 2
- Serine/threonine-protein kinase/endoribonuclease IRE1 2
- Phosphatidylinositol 3-kinase C2 domain-containing subunit gamma 2
- Ankyrin repeat and protein kinase domain-containing protein 1 2
- Tyrosine-protein kinase Lyn 2
- Focal adhesion kinase 1 2
- Tyrosine-protein kinase TXK 2
- Rhodopsin kinase GRK7 2
- Ephrin type-A receptor 8 2
- Phosphatidylinositol 4-kinase beta 2
- Death-associated protein kinase 2 2
- Death-associated protein kinase 1 2
- Serine/threonine-protein kinase D2 2
- Serine/threonine-protein kinase D3 2
- TGF-beta receptor type-2 2
- Serine/threonine-protein kinase D1 2
- Dual specificity tyrosine-phosphorylation-regulated kinase 1B 2
- Dual specificity tyrosine-phosphorylation-regulated kinase 1A 2
- Death-associated protein kinase 3 2
- Cyclin-dependent kinase 9 2
- Cyclin-dependent kinase 8 2
- Serine/threonine-protein kinase pim-3 2
- Cyclin-dependent kinase 7 2
- Serine/threonine-protein kinase pim-1 2
- Cyclin-dependent kinase 5 2
- Serine/threonine-protein kinase pim-2 2
- Serine/threonine-protein kinase 38 2
- Cyclin-dependent kinase 4 2
- Serine/threonine-protein kinase 35 2
- Cyclin-dependent kinase 3 2
- Serine/threonine-protein kinase 36 2
- Testis-specific serine/threonine-protein kinase 1 2
- Cyclin-dependent kinase 16 2
- Protein kinase C epsilon type 2
- Cyclin-dependent kinase 17 2
- Bone morphogenetic protein receptor type-2 2
- Cyclin-dependent kinase 19 2
- Protein-tyrosine kinase 6 2
- Casein kinase II subunit alpha 2
- Cyclin-dependent kinase 14 2
- Cyclin-dependent kinase 15 2
- Leukocyte tyrosine kinase receptor 2
- Cytoplasmic tyrosine-protein kinase BMX 2
- Tyrosine-protein kinase ABL2 2
- Atypical kinase COQ8B, mitochondrial 2
- Microtubule-associated serine/threonine-protein kinase 1 2
- Calcium/calmodulin-dependent protein kinase type II subunit alpha 2
- cGMP-dependent protein kinase 2 2
- Rho-associated protein kinase 2 2
- cGMP-dependent protein kinase 1 2
- Rho-associated protein kinase 1 2
- Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform 2
- Serine/threonine-protein kinase ULK1 2
- Serine/threonine-protein kinase SIK2 2
- Tyrosine-protein kinase Fes/Fps 2
- Serine/threonine-protein kinase SIK1 2
- Serine/threonine-protein kinase ULK2 2
- Serine/threonine-protein kinase ULK3 2
- 3-phosphoinositide-dependent protein kinase 1 2
- Mitogen-activated protein kinase 1 2
- Serine/threonine-protein kinase 3 2
- Mitogen-activated protein kinase 3 2
- Mitogen-activated protein kinase 4 2
- Serine/threonine-protein kinase 4 2
- SRSF protein kinase 3 2
- Mitogen-activated protein kinase 9 2
- SRSF protein kinase 2 2
- Mitogen-activated protein kinase 6 2
- Mitogen-activated protein kinase 7 2
- Mitogen-activated protein kinase 8 2
- Calcium/calmodulin-dependent protein kinase type IV 2
- Tyrosine-protein kinase SYK 2
- Serine/threonine-protein kinase TBK1 2
- Serine/threonine-protein kinase RIO1 2
- Serine/threonine-protein kinase LATS1 2
- Serine/threonine-protein kinase RIO3 2
- Serine/threonine-protein kinase 32B 2
- Serine/threonine-protein kinase RIO2 2
- Serine/threonine-protein kinase 32C 2
- Insulin receptor 2
- Tyrosine-protein kinase HCK 2
- Serine/threonine-protein kinase PLK1 2
- Serine/threonine-protein kinase PLK2 2
- Insulin receptor-related protein 2
- Inhibitor of nuclear factor kappa-B kinase subunit beta 2
- Serine/threonine-protein kinase PLK3 2
- Serine/threonine-protein kinase NIM1 2
- Serine/threonine-protein kinase PLK4 2
- Tyrosine-protein kinase receptor TYRO3 2
- Wee1-like protein kinase 2 2
- Serine/threonine-protein kinase BRSK1 2
- Serine/threonine-protein kinase LATS2 2
- Citron Rho-interacting kinase 2
- Serine/threonine-protein kinase BRSK2 2
- Serine/threonine-protein kinase Chk2 2
- Serine/threonine-protein kinase Chk1 2
- cAMP-dependent protein kinase catalytic subunit PRKX 2
- Tyrosine-protein kinase Yes 2
- Serine/threonine-protein kinase MRCK beta 2
- Serine/threonine-protein kinase MRCK gamma 2
- Casein kinase II subunit alpha' 2
- Dual specificity tyrosine-phosphorylation-regulated kinase 2 2
- Serine/threonine-protein kinase STK11 2
- Cyclin-G-associated kinase 2
- Receptor tyrosine-protein kinase erbB-4 2
- Tyrosine-protein kinase FRK 2
- Receptor tyrosine-protein kinase erbB-2 2
- Receptor tyrosine-protein kinase erbB-3 2
- Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform 2
- Serine/threonine-protein kinase Nek9 2
- Serine/threonine-protein kinase Nek7 2
- Glycogen synthase kinase-3 alpha 2
- Serine/threonine-protein kinase Nek6 2
- Serine/threonine-protein kinase Nek5 2
- Serine/threonine-protein kinase Nek2 2
- Serine/threonine-protein kinase Nek1 2
- Serine/threonine-protein kinase receptor R3 2
- Macrophage-stimulating protein receptor 2
- Cyclin-dependent kinase-like 3 2
- Cyclin-dependent kinase-like 2 2
- Serine/threonine-protein kinase SIK3 [59-1321] 2
- MAP/microtubule affinity-regulating kinase 3 2
- Homeodomain-interacting protein kinase 4 2
- Homeodomain-interacting protein kinase 3 2
- MAP kinase-interacting serine/threonine-protein kinase 2 2
- MAP kinase-interacting serine/threonine-protein kinase 1 2
- Cyclin-dependent kinase-like 5 2
- Membrane-associated tyrosine- and threonine-specific cdc2-inhibitory kinase 2
- MAP/microtubule affinity-regulating kinase 4 2
- Serine/threonine-protein kinase 10 2
- Serine/threonine-protein kinase 38-like 2
- Dual specificity protein kinase TTK 2
- Myosin-IIIb 2
- Myosin-IIIa 2
- Tyrosine-protein kinase ITK/TSK 2
- Myotonin-protein kinase 2
- Protein kinase C eta type 2
- Bone morphogenetic protein receptor type-1B 2
- Bone morphogenetic protein receptor type-1A 2
- Receptor-interacting serine/threonine-protein kinase 2 2
- Serine/threonine-protein kinase 16 2
- Non-receptor tyrosine-protein kinase TNK1 2
- Inhibitor of nuclear factor kappa-B kinase subunit epsilon 2
- Serine/threonine-protein kinase NLK 2
- Homeodomain-interacting protein kinase 2 2
- Homeodomain-interacting protein kinase 1 2
- Receptor-interacting serine/threonine-protein kinase 4 2
- Ribosomal protein S6 kinase beta-1 2
- Serine/threonine-protein kinase OSR1 2
- Casein kinase I isoform delta 2
- Cyclin-dependent kinase 18 [3-474] 2
- RAF proto-oncogene serine/threonine-protein kinase 2
- Serine/threonine-protein kinase 26 2
- Serine/threonine-protein kinase 24 2
- Dual specificity testis-specific protein kinase 1 2
- Serine/threonine-protein kinase 25 2
- Ephrin type-B receptor 3 2
- Serine/threonine-protein kinase 33 2
- Ephrin type-B receptor 4 2
- Ephrin type-B receptor 1 2
- Ephrin type-B receptor 2 2
- Ephrin type-B receptor 6 2
- MAP kinase-activated protein kinase 2 2
- MAP kinase-activated protein kinase 5 2
- STE20/SPS1-related proline-alanine-rich protein kinase 2
- Muscle, skeletal receptor tyrosine-protein kinase 2
- Tyrosine-protein kinase Fer 2
- 5'-AMP-activated protein kinase catalytic subunit alpha-2 2
- Tyrosine-protein kinase receptor Tie-1 2
- Calcium/calmodulin-dependent protein kinase type II subunit delta 2
- Proto-oncogene tyrosine-protein kinase ROS 2
- Calcium/calmodulin-dependent protein kinase kinase 1 2
- Serine/threonine-protein kinase DCLK1 2
- Serine/threonine-protein kinase TAO3 2
- Calcium/calmodulin-dependent protein kinase kinase 2 2
- Serine/threonine-protein kinase DCLK2 2
- Serine/threonine-protein kinase DCLK3 2
- Angiopoietin-1 receptor 2
- Serine/threonine-protein kinase TNNI3K 2
- Interferon-induced, double-stranded RNA-activated protein kinase 2
- Mitogen-activated protein kinase kinase kinase kinase 2 2
- Mitogen-activated protein kinase kinase kinase kinase 3 2
- Mitogen-activated protein kinase kinase kinase kinase 1 2
- Serine/threonine-protein kinase MRCK alpha 2
- Mitogen-activated protein kinase kinase kinase kinase 4 2
- Mitogen-activated protein kinase kinase kinase kinase 5 2
- Mitogen-activated protein kinase 15 2
- 5'-AMP-activated protein kinase catalytic subunit alpha-1 2
- Activin receptor type-1B 2
- Myosin light chain kinase family member 4 2
- Mitogen-activated protein kinase kinase kinase 9 2
- RAC-gamma serine/threonine-protein kinase 2
- Mitogen-activated protein kinase kinase kinase 6 2
- Mitogen-activated protein kinase kinase kinase 5 2
- Interleukin-1 receptor-associated kinase 3 2
- Mitogen-activated protein kinase kinase kinase 7 2
- Mitogen-activated protein kinase kinase kinase 2 2
- Mitogen-activated protein kinase kinase kinase 1 2
- Mitogen-activated protein kinase kinase kinase 4 2
- Mitogen-activated protein kinase kinase kinase 3 2
- Serine/threonine-protein kinase ICK 2
- RAC-alpha serine/threonine-protein kinase 2
- Megakaryocyte-associated tyrosine-protein kinase 2
- Proto-oncogene tyrosine-protein kinase Src 2
- Activin receptor type-2B 2
- Activin receptor type-2A 2
- BDNF/NT-3 growth factors receptor 2
- Serine/threonine-protein kinase 17A 2
- Serine/threonine-protein kinase 17B 2
- Mitogen-activated protein kinase kinase kinase 19 2
- Dual specificity protein kinase CLK1 2
- Mitogen-activated protein kinase kinase kinase 15 2
- Protein kinase C delta type 2
- NT-3 growth factor receptor 2
- Dual specificity protein kinase CLK4 2
- G protein-coupled receptor kinase 4 2
- Dual specificity protein kinase CLK3 2
- Dual specificity protein kinase CLK2 2
- Protein-tyrosine kinase 2-beta 2
- High affinity nerve growth factor receptor 2
- Tyrosine-protein kinase Mer 2
- Serine/threonine-protein kinase N2 2
- cAMP-dependent protein kinase catalytic subunit beta 2
- Serine/threonine-protein kinase N1 2
- Ribosomal protein S6 kinase alpha-3 2
- Calcium/calmodulin-dependent protein kinase type 1D 2
- Phosphorylase b kinase gamma catalytic chain, liver/testis isoform 2
- STE20-like serine/threonine-protein kinase 2
- Hormonally up-regulated neu tumor-associated kinase 2
- Fibroblast growth factor receptor 4 2
- Tyrosine-protein kinase Fgr 2
- Aurora kinase B 2
- Mitogen-activated protein kinase kinase kinase 20 2
- Fibroblast growth factor receptor 1 2
- Phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta 2
- Fibroblast growth factor receptor 2 2
- Atypical kinase COQ8A, mitochondrial 2
- Aurora kinase C 2
- Mitogen-activated protein kinase 13 2
- Mitogen-activated protein kinase 12 2
- Inhibitor of nuclear factor kappa-B kinase subunit alpha 2
- Mitogen-activated protein kinase 11 2
- Phosphatidylinositol 4-phosphate 5-kinase type-1 alpha 2
- RAC-beta serine/threonine-protein kinase 2
- Mitogen-activated protein kinase 10 2
- Casein kinase I isoform alpha 2
- Misshapen-like kinase 1 2
- Tyrosine-protein kinase Fyn 2
- Tyrosine-protein kinase CSK 2
- Maternal embryonic leucine zipper kinase 2
- Serine/threonine-protein kinase MARK1 2
- Serine/threonine-protein kinase MARK2 2
- TRAF2 and NCK-interacting protein kinase 2
- Mitogen-activated protein kinase kinase kinase 13 2
- Mitogen-activated protein kinase kinase kinase 10 2
- Mitogen-activated protein kinase kinase kinase 11 2
- Calcium-dependent protein kinase 1 1
- Serine/threonine-protein kinase Nek11 1
- Cyclin-A1/Cyclin-dependent kinase 2 1
- Peripheral plasma membrane protein CASK 1
- Serine/threonine-protein kinase mTOR 1
- Eukaryotic translation initiation factor 2-alpha kinase 1 1
- Dual serine/threonine and tyrosine protein kinase 1
- Phosphatidylinositol 5-phosphate 4-kinase type-2 gamma 1
- Poly [ADP-ribose] polymerase tankyrase-2 1
- Serine/threonine-protein kinase PknB 1
- Receptor-type tyrosine-protein kinase FLT3 [D835H] 1
- SNF-related serine/threonine-protein kinase 1
- Serine/threonine-protein kinase PRP4 homolog 1
- Serine/threonine-protein kinase TAO2 1
- Cyclin-dependent kinase-like 1 [2-358] 1
- Cyclin-dependent kinase 2 homolog 1
- Casein kinase I isoform alpha-like 1
- Calcium/calmodulin-dependent protein kinase type 1G 1
- Serine/threonine-protein kinase 32A 1
- Cyclin-dependent kinase 13 1
- Protein kinase C iota type 1
- Transient receptor potential cation channel subfamily M member 6 1
- Serine/threonine-protein kinase Nek4 1
- U4/U6 small nuclear ribonucleoprotein Prp4 1
- Serine/threonine-protein kinase Nek3 1
- Serine/threonine-protein kinase VRK2 1
- cAMP-dependent protein kinase catalytic subunit alpha 1
- Protein kinase C alpha type 1
- eIF-2-alpha kinase GCN2 1
- Phosphatidylinositol 4-phosphate 5-kinase type-1 gamma 1
- Receptor-type tyrosine-protein kinase FLT3 [N841I] 1
- Dimer of Receptor-type tyrosine-protein kinase FLT3 [F691L] 1
- Serine/threonine-protein kinase SBK1 1
- Receptor-type tyrosine-protein kinase FLT3 [564-710,762-958] 1
- Protein delta homolog 1 1
- Activated CDC42 kinase 1 1
- Dual specificity mitogen-activated protein kinase kinase 7 1
- Dual specificity mitogen-activated protein kinase kinase 5 1
- Mitogen-activated protein kinase kinase kinase 12 1
- Receptor-type tyrosine-protein kinase FLT3 [D835V] 1
- Receptor-type tyrosine-protein kinase FLT3 [R834Q] 1
- Serine/threonine-protein kinase Sgk3 1
- Dimer of Receptor-type tyrosine-protein kinase FLT3 [D835V] 1
- Myosin light chain kinase 3 1
- ...
Publications 35▿
- Nat Biotechnol 29: 1046-51 (2011) 442
- Blood 114: 2984-92 (2009) 361
- US Patent US11542261 (2023) 36
- J Med Chem 60: 8407-8424 (2017) 10
- ACS Med Chem Lett 11: 1567-1572 (2020) 10
- J Med Chem 52: 7808-16 (2009) 10
- J Med Chem 53: 6779-810 (2010) 6
- Eur J Med Chem 184: (2019) 5
- J Med Chem 59: 6187-200 (2016) 5
- Bioorg Med Chem Lett 22: 4654-9 (2012) 4
- Bioorg Med Chem Lett 30: (2020) 3
- Eur J Med Chem 100: 151-61 (2015) 3
- Bioorg Med Chem 48: (2021) 3
- J Med Chem 61: 3855-3869 (2018) 3
- J Med Chem 62: 2428-2446 (2019) 3
- J Med Chem 62: 9141-9160 (2019) 3
- Eur J Med Chem 193: (2020) 3
- Bioorg Med Chem Lett 60: (2022) 3
- Bioorg Med Chem 56: (2022) 2
- Eur J Med Chem 235: (2022) 2
- ACS Med Chem Lett 7: 476-81 (2016) 2
- Bioorg Med Chem 21: 2856-67 (2013) 2
- J Med Chem 64: 10981-10996 (2021) 2
- Eur J Med Chem 85: 399-407 (2014) 2
- US Patent US9216997 (2015) 1
- J Med Chem 65: 14971-14999 (2022) 1
- J Med Chem 62: 4158-4173 (2019) 1
- Bioorg Med Chem Lett 27: 496-500 (2017) 1
- Bioorg Med Chem Lett 30: (2020) 1
- Eur J Med Chem 94: 123-31 (2015) 1
- Eur J Med Chem 195: (2020) 1
- Eur J Med Chem 120: 74-85 (2016) 1
- Eur J Med Chem 182: (2019) 1
- US Patent US10266535 (2019) 1
- Bioorg Med Chem Lett 24: 2655-60 (2014) 1
Institutions 26▿
- Ambit Biosciences 813
- Children'S Hospital Medical Center 36
- Chinese Academy of Sciences 10
- Jinan University 10
- National Health Research Institutes 9
- Palack£ 7
- Aristotle University Of Thessaloniki 6
- East China University Of Science & Technology 5
- Vichem Chemie Research 5
- Yonsei University 5
- Korea University 3
- Technische Universit£T Darmstadt 3
- University Of Regensburg 3
- Chinese Academy Of Sciences 3
- Sichuan University 3
- Ain Shams University 2
- University Of Palermo 2
- Purdue University 2
- Harvard Medical School 2
- West China Hospital 1
- TBA 1
- The University Of Arizona 1
- Gwangju Institute Of Science And Technology 1
- Hefei Institutes of Physical Science, Chinese Academy of Sciences 1
- Shanghai De Novo Pharmatech 1
- Jiangnan University 1
Affinity: 0.0020 to 3.0E+4 nM▿
- IC50 83
- Kd 857
- Affinity ≤ nM
Xtal structures: 1
Docked structures: 0
Catalog Cmpds: 1