BDBM50301217 4-(4-fluoro-5-methoxy-1-(4-(trifluoromethyl)benzyl)-2,3,3a,7a-tetrahydro-1H-inden-1-yl)-1-methyl-1H-imidazol-2-amine::CHEMBL582982

SMILES COC1=C(F)C2CCC(Cc3ccc(cc3)C(F)(F)F)(C2C=C1)c1cn(C)c(N)n1

InChI Key InChIKey=WWWWZFLJGIDVFC-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50301217   

TargetBeta-secretase 1(Homo sapiens (Human))
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50301217(4-(4-fluoro-5-methoxy-1-(4-(trifluoromethyl)benzyl...)
Affinity DataIC50:  63nMAssay Description:Inhibition of BACE-1More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed