BDBM50302593 1-(4-methoxy-2-methylphenyl)-N-(2-methoxyethyl)-3,6-dimethyl-N-propyl-1H-pyrazolo[3,4-d]pyrimidin-4-amine::CHEMBL568606

SMILES CCCN(CCOC)c1nc(C)nc2n(nc(C)c12)-c1ccc(OC)cc1C

InChI Key InChIKey=DXVNLEPWBPMCOF-UHFFFAOYSA-N

Data  2 KI  1 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50302593   

TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50302593(1-(4-methoxy-2-methylphenyl)-N-(2-methoxyethyl)-3,...)
Affinity DataKi:  13nMAssay Description:Antagonist activity at human recombinant CRF1 receptor expressed in CHO cells assessed as inhibition of CRF-induced cAMP productionMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50302593(1-(4-methoxy-2-methylphenyl)-N-(2-methoxyethyl)-3,...)
Affinity DataKi:  13nMAssay Description:Antagonist activity at recombinant human CRF1 receptor expressed in CHO cells assessed as inhibition of CRF-induced cAMP formationMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Homo sapiens (Human))
Pfizer

Curated by ChEMBL
LigandPNGBDBM50302593(1-(4-methoxy-2-methylphenyl)-N-(2-methoxyethyl)-3,...)
Affinity DataKd:  14nMAssay Description:Binding affinity to recombinant human CRF1 receptor expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed