BDBM50303385 CHEMBL566064::N-(4-(4-(azepan-1-ylsulfonyl)phenyl)thiazol-2-yl)thiophene-2-carboxamide::cid_1161245

SMILES O=C(Nc1nc(cs1)-c1ccc(cc1)S(=O)(=O)N1CCCCCC1)c1cccs1

InChI Key InChIKey=SULMLRBYXGQSKE-UHFFFAOYSA-N

Data  2 IC50  3 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50303385   

TargetNuclear receptor coactivator 3(Homo sapiens (Human))
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM50303385(CHEMBL566064 | N-(4-(4-(azepan-1-ylsulfonyl)phenyl...)
Affinity DataEC50:  1.74E+4nMAssay Description:Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center http://molscreen.florida.scripps.edu/ Center Affiliation: The ...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetNuclear receptor coactivator 2(Homo sapiens (Human))
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM50303385(CHEMBL566064 | N-(4-(4-(azepan-1-ylsulfonyl)phenyl...)
Affinity DataEC50:  1.46E+4nMAssay Description:Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute (TSRI) Assay...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay
TargetCruzipain(Trypanosoma cruzi)
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM50303385(CHEMBL566064 | N-(4-(4-(azepan-1-ylsulfonyl)phenyl...)
Affinity DataIC50: >6.00E+4nMAssay Description:Inhibition of Tryapanosom cruzi cruzain by quantitative high throughput screeningMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCruzipain(Trypanosoma cruzi)
National Human Genome Research Institute

Curated by ChEMBL
LigandPNGBDBM50303385(CHEMBL566064 | N-(4-(4-(azepan-1-ylsulfonyl)phenyl...)
Affinity DataIC50:  1.20E+4nMAssay Description:Inhibition of Tryapanosom cruzi cruzain by Flexstation microplate spectrofluorometryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNuclear receptor coactivator 1(Homo sapiens (Human))
The Scripps Research Institute Molecular Screening Center

Curated by PubChem BioAssay
LigandPNGBDBM50303385(CHEMBL566064 | N-(4-(4-(azepan-1-ylsulfonyl)phenyl...)
Affinity DataEC50:  1.65E+4nMAssay Description:Source (MLSCN Center Name): The Scripps Research Institute Molecular Screening Center Center Affiliation: The Scripps Research Institute (TSRI) Assay...More data for this Ligand-Target Pair
In DepthDetails PCBioAssay